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Composition for preventing or treating renal fibrosis comprising dimethylfumarate as active ingredient

机译:以富马酸二甲酯为有效成分的预防或治疗肾纤维化的组合物

摘要

The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-β/Smad signaling, and thus is useful for preventing or treating renal fibrosis.
机译:本发明涉及一种用于预防或治疗肾纤维化的组合物,其包含富马酸二甲酯(DMF)作为活性成分。根据本发明的DMF通过激活Nrf2以抑制TGF-β/ Smad信号转导而具有降低肾纤维化的优异效果,因此可用于预防或治疗肾纤维化。

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