Recombinant outer membrane proteins from Brachyspira hyodysenteriae and uses thereof

摘要

The present invention relates generally to the field of diarrheal diseases caused by intestinal spirochaetes. Specifically, the invention relates to the prevention and/or treatment of infections with B. hyodysenteriae. In one aspect, the invention relates to a novel recombinant polypeptide, wherein said polypeptide may preferably be combined with one or more further recombinant polypeptides. In a further aspect, an immunogenic composition containing said recombinant polypeptide(s) is provided for use in a method for treating or preventing clinical signs caused by Brachyspira hyodysenteriae.