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Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples

机译:用于冷冻等分试样的机器人末端执行器以及从生物样品中提取冷冻等分试样的方法

摘要

A robotic end effector for collecting frozen aliquots from an array of frozen samples in a plurality of containers has a coring bit for taking frozen sample cores from the frozen samples and a frozen sample core extraction system adapted to extract frozen sample cores from the frozen samples. A fill level detection system is adapted to detect the positions of the surfaces of the frozen samples. A processor is adapted to receive signals from the fill level detection system and use the signals and information concerning operation of the frozen sample core extraction system to determine at least one of the following: (a) the amount of material contained in a frozen sample core obtained by the coring bit; and (b) the number of frozen sample cores needed from a particular frozen sample to obtain a predetermined amount of material from that frozen sample.
机译:用于从多个容器中的一系列冷冻样品中收集冷冻等分试样的自动末端执行器具有用于从冷冻样品中取出冷冻样品芯的取芯钻头,以及适于从冷冻样品中提取冷冻样品芯的冷冻样品芯提取系统。填充水平检测系统适于检测冷冻样品表面的位置。处理器适于从填充水平检测系统接收信号,并使用与冷冻样品芯提取系统的操作有关的信号和信息来确定以下至少一项:(a)冷冻样品芯中包含的材料量通过取芯钻头获得; (b)从特定的冷冻样品中获取预定数量的材料所需的冷冻样品芯的数量。

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