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Probiotic gram-positive bacteria for the prophylaxis, suppression, or elimination of allergic reactions in human

机译:益生菌革兰氏阳性细菌,用于预防,抑制或消除人的过敏反应

摘要

A method for a prophylaxis, suppression or elimination of an allergic reaction in a human, or for shifting the TH1-TH2 balance in a human body toward an increase of TH1 or a decrease of TH2 or both an increase in TH1 and a decrease in TH2, includes the steps of preparing a pharmaceutical composition having genomic DNA of at least one probiotic, gram-positive bacteria strain selected from the group Lactobacillus gasseri PA 16/8, Bifidobacterium bifidum MF 20/5, Bifidobacterium bifidum MG 20/5, Bifidumbacterium longum SP 07/3, Lactobacillus rhamnosus GG (92164) or a combination thereof, as an active ingredient, the at least one probiotic, gram-positive bacteria strain being present in the form of at least one of viable bacteria and inactivated bacteria, and administering to a human as suppository, vaginally, as a cream applied to skin, rectally, as a subcutaneous injection, as intravenous injection, as an inhalation liquid, or orally in combination with food.
机译:一种预防,抑制或消除人的过敏反应,或将人体内TH1-TH2平衡转移至TH1升高或TH2降低,或TH1升高和TH2降低两者的方法包括制备具有至少一种选自以下组的益生菌,革兰氏阳性细菌菌株的基因组DNA的药物组合物的步骤:格氏乳酸杆菌PAI 16/8,双歧杆菌双歧杆菌 MF 20/5,双歧杆菌 MG 20/5,长双歧杆菌 SP 07/3,鼠李糖乳杆菌 GG(92164)或它们的组合作为活性成分,所述至少一种革兰氏阳性益生菌菌株以活菌和灭活细菌中的至少一种形式存在,并以阴道栓剂的形式经阴道施用给人,作为乳膏剂应用于皮肤,直肠,皮下注射,静脉内注射,吸入液体或口服与 餐饮。

著录项

  • 公开/公告号US9644210B2

    专利类型

  • 公开/公告日2017-05-09

    原文格式PDF

  • 申请/专利权人 JÜRGEN SCHREZENMEIR;

    申请/专利号US201314089502

  • 发明设计人 JÜRGEN SCHREZENMEIR;

    申请日2013-11-25

  • 分类号A61K35/74;C12N15/11;C12N15/117;A61K35/741;

  • 国家 US

  • 入库时间 2022-08-21 13:42:08

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