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AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors
AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors
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机译:AAV1-caspase基因治疗诱导的细胞凋亡治疗肿瘤
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摘要
Described herein are compositions and methods for treating, inhibiting, preventing, reducing the severity of and/or reducing the progression of schwannoma, as well as any disease or physiological disease-state in which schwannoma plays a role. The compositions comprise an rAAV vector that includes a caspase-1 gene or a variant thereof and a Schwann cell specific promoter.
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