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Quantitative in situ characterization of heterogeneity in biological samples
Quantitative in situ characterization of heterogeneity in biological samples
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机译:生物样品中异质性的定量原位表征
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摘要
The present disclosure relates to characterization of biological samples. By way of example, a biological sample may be contacted with a plurality of probes specific for targets in the sample, such as probes for immune markers and segmenting probes. Acquired image data of the sample may be used to segment the images into epithelial and stromal regions to characterize individual cells in the sample based on the binding of the probes. Further, the biological sample may be characterized by a heterogeneity of the characterized cells.
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