use of lysosomal acid lipase for treatment of lysosomal acid lipase deficiency in patients

摘要

Use of lysosomal acid lipase for treatment of lissomal acid lipase deficiency in patients. The present invention provides treatment for lal deficiency (e.g., wolman's disease, cesd) comprising administering to a mammal a therapeutically effective amount of lysosomal acid lipase at an effective dosage frequency. Methods of enhancing liver growth and function, increasing tissue lal concentration and increasing lal activity in a human patient suffering from lal deficiency are also provided.