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Method to treat chronic kidney disease and degenerative diseases related to the patient's age

机译:治疗与患者年龄有关的慢性肾脏疾病和退行性疾病的方法

摘要

The present invention is directed to a method for treating a patient suffering from a metabolic disorder such as the metabolic syndrome, Type 2 diabetes, obesity, or prediabetes, and the metabolic sequale of these diseases including cardiovascular, cerebrovascular, renal and hepatic diseases, comprising the step of: administering to a patient suffering from the metabolic syndrome, Type 2 diabetes, obesity, or prediabetes a pharmaceutical composition comprising (1) at least one compound that stimulates an increase in central dopaminergic neuronal activity level in the subject, and (2) at least one compound that stimulates a decrease in central noradrenergic neuronal activity level in the subject.
机译:本发明涉及治疗患有代谢紊乱例如代谢综合征,2型糖尿病,肥胖或糖尿病前期的患者以及这些疾病包括心血管,脑血管,肾和肝病的代谢后遗症的方法,所述方法包括:步骤:向患有代谢综合症,2型糖尿病,肥胖症或糖尿病前期的患者给药药物组合物,该药物组合物包含(1)至少一种刺激受试者中枢多巴胺能神经元活性水平增加的化合物,和(2) )至少一种刺激受试者中枢去甲肾上腺素能神经元活性水平降低的化合物。

著录项

  • 公开/公告号BR112013012212A2

    专利类型

  • 公开/公告日2017-11-07

    原文格式PDF

  • 申请/专利权人 VEROSCIENCE LLC;

    申请/专利号BR20131112212

  • 发明设计人 ANTHONY H. CINCOTTA;

    申请日2011-11-21

  • 分类号A61K31/497;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:48

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