Nuclu00eaicos acids useful for integration within, and expression of gene in the Archaea hipertermu00f3fila and acidu00f3fila

摘要

Abstract invention patent: "nuclu00eaicos acids useful for integration within, and expression of gene in the Archaea hipertermu00f3fila and acidu00f3fila".The present invention relates to a new recombinant or isolated nucleic acid useful for being integrated in a Archaea or a eubactu00e9ria acidu00f3fila or hyper thermophilic useful to be integradOr be maintained in a Archaea or eubactu00e9ria acidu00f3fila or hyper thermophilic.The nucleic acid encodes a sequence of nucleotides that is able to integrate stably within the chromosome of the host cell.Or being held as an element extracromossoma in a host cell, which is a archaea, and a sequence of nucleotides of interest.This invention also provides a host cell comprising the nucleic acid Archaea integrated mode stable within the chromosome or maintained in a manner episu00f4micamente in cell hospedThe threshing floor, and a method for expression of the nucleotide sequence of interest in the host cell and / or directing the glycosylation, multimerizau00e7u00e3o and / or the combination or integration of the membrane.