pyridone derivatives and their uses in the treatment of tuberculosis

摘要

Patent Summary: "Pyridone derivatives and uses thereof for the treatment of tuberculosis". A compound of formula (i) (i) has been shown to be useful for the treatment of a disease, disorder or syndrome which is mediated by inhibition of mycolic acid biosynthesis by inhibition of carrier protein reductase enzyme. of enoyl acyl from m. tuberculosis (inha): wherein r1, r2, r3, r4 and r5 are as defined herein.