compositions comprising selenium and their use for the treatment and prevention of disease or conditions associated with mitochondrial dysfunction

摘要

abstract the present application relates to compositions comprising selenium (e.g., selenium enriched yeast and selenium containing compounds obtained or derived therefrom) and methods of using the same to treat and inhibit obesity, diabetes and related conditions. in particular, the present application provides compositions comprising selenium enriched yeast (eg, selenium enriched yeast comprising 2% or less inorganic selenium), selenium containing compounds present therein and / or derived therefrom, and methods of using the same to enhance mitochondrial activity and function (eg, skeletal muscle and liver) in a subject (eg, a therapeutic and / or prophylactic treatment for diabetes, obesity and related conditions). "compositions comprising selenium and their use for the treatment and prevention of disease or conditions associated with mitochondrial dysfunction" The present invention relates to compositions comprising selenium (e.g. selenium enriched yeast and selenium-containing compounds obtained or derived from them) and methods for using them to treat and inhibit obesity, diabetes and related conditions. in particular, the present application provides compositions comprising selenium enriched yeast (e.g., selenium enriched yeast comprising 2% or less inorganic selenium), selenium containing compounds present therein and / or derivatives thereof and methods for using the same to improve mitochondrial activity and function (eg, skeletal muscle and liver) in an individual (eg as a therapeutic and / or prophylactic treatment for diabetes, obesity and related conditions). 1/1