trials and methods to select a treatment regimen for an individual with depression

摘要

Patents and Methods for Selecting a Treatment Regimen for a Depressed Individual. The present invention relates to assays, methods and compositions for selecting a treatment regimen for a patient having depression or at risk for depression and / or treating at least one depression symptom in the individual, based on the recognition that specific combinations of polymorphisms. single nucleotide (snps) are associated with a therapeutic response to a compound comprising folate. provided herein are likewise methods for improving the effectiveness of an antidepressant drug administered to an individual with depression or at risk for depression by administering adjunctive therapy of a folate-comprising compound to the individual if the individual carries a specific combination of snps which is predictable outcome of a therapeutic response. further provided herein are compositions of the compound comprising folate.