1 - ((3S, 4R) - 4 - (3-fluorophenyl) - 1 - (2-methoxyethyl) pyrrolidin-3-yl) - 3 - (4 - methyl - 3 - (2 - metilpirimidin - il - 5 - 1 - phenyl) - 1H pyrazole - 5 - il) urea TrkA Kinase Inhibitor.

摘要

Compound 1 - ((3S, 4R) - 4 - (3-fluorooctane sulfonic acid) - 1 - (2-methoxy) pyridine-3-ll) - 3 - (4-methyl-3 - (2-methylpyridine-5-il) - 1-phenyl-1h-pyrazol-5-il) urea, TrkA cinasa inhibitor; preparation process; drug composition of the substance; and treatment of pain, cncre, inflammation, neurodegenerative diseases, etc.Integrated image 2Or a pharmaceutically acceptable salt, which is a cyclopropane inhibitor that helps to treat diseases that can be treated with cyclopropane inhibitors, such as pain, cancer, inflammation and inflammation, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, Endocrine, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome, morbid