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Biotinylated triterpenes of the lupane type and their use
Biotinylated triterpenes of the lupane type and their use
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机译:卢潘型生物素化三萜及其用途
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摘要
ufeffbiotinylovanu00e9 triterpenes lupanovu00e9ho type (general formula (i), where the symbol l is composed of a uhlu00edkatu00fdm chain with 10 to 40 carbon atoms with simple or one or more di or one or more trojnu00fdmi ties and the chondrites chain may contain one or knows ce karbonylovu00fdch groups or one or more carbon atoms in the uhlu00edkatu00e9m chain may be substituovu00e1no atom oxygensulphur or u2013nh - group. biotinylovanu00e9 triterpenes lupanovu00e9ho type of general formula i are conjugates, i. active triterpenic esters (potential anticancer agents) with biotinem and are useful in the pharmaceutical industry for the determination of the molecular targets of these triterpenic esters.with their use, is using the methods afinitnu00ed chromatography, pull down the essays, and quantitative proteomiky in combination with the method silac possible to identify the proteins with which these, i. active triterpenes specifically interact or which inhibit and to clarify the mechanism effect these anticancer triterpenic esters.
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