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SUBSTITUTED BISPHENYL BUTANOIC ACID DERIVATIVES AS NEP INHIBITORS WITH IMPROVED IN VIVO EFFICACY
SUBSTITUTED BISPHENYL BUTANOIC ACID DERIVATIVES AS NEP INHIBITORS WITH IMPROVED IN VIVO EFFICACY
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机译：取代的联苯二酚丁二酸衍生物作为NEEP抑制剂，体内功效得到改善
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摘要
The present invention provides a compound of formula I; ;or a pharmaceutically acceptable salt thereof, wherein X is defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a pharmaceutical composition of the compounds of the invention and a combination of pharmacologically active agents and a compound of the invention.
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机译：本发明提供了式I的化合物; <图像文件=“ IMGA0002.GIF” he =“ 57” imgContent =“绘图” imgFormat =“ GIF” wi =“ 49” /> ;或其药学上可接受的盐，其中X在本文中定义。本发明还涉及制备本发明化合物的方法及其治疗用途。本发明进一步提供了本发明化合物的药物组合物以及药理活性剂和本发明化合物的组合。
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