APPLICATION OF DOUBLE AGONIST OF GLP-1 / GLYCAGON RECEPTORS FOR PROLONGED ACTION FOR THE TREATMENT OF NON-ALCOHOLIC LIVER DISEASE

摘要

The present invention relates to a pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease, comprising a prolonged action double GLP-1 / glucagon receptor agonist, and a method for the prevention or treatment of non-alcoholic fatty liver disease, including administration of the composition. The composition of the present invention either does not have a side effect in the form of weight gain, or reduces a side effect in the form of weight gain, which is a side effect of using standard medicines to treat non-alcoholic fatty liver disease, and also reduces the number of GLP-1 / glucagon receptor double agonist injections prolonged action, thus greatly increasing the convenience for the patient. In addition, the GLP-1 / glucagon double receptor agonist of the prolonged action of the present invention improves in vivo reliability and stability