首页> 外国专利> BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXENE DERIVATIVE COMPOUNDS AS CETP INHIBITORS

BIARYL- OR HETEROCYCLIC BIARYL-SUBSTITUTED CYCLOHEXENE DERIVATIVE COMPOUNDS AS CETP INHIBITORS

机译:作为CETP抑制剂的双环或杂环双环取代的环己烯衍生物

摘要

The present invention provides biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds, isomers thereof, or pharmaceutically acceptable salts. The compounds of the invention show a CETP inhibitory effect that increases HDL-cholesterol levels and reduces LDL-cholesterol levels. Pharmaceutical compositions comprising the compounds are useful for the prevention or treatment of dyslipidemia or dyslipidemia-related diseases.
机译:本发明提供联芳基或杂环联芳基取代的环己烯衍生物化合物,其异构体或药学上可接受的盐。本发明的化合物显示出CETP抑制作用,其增加HDL-胆固醇水平并降低LDL-胆固醇水平。包含所述化合物的药物组合物可用于预防或治疗血脂异常或与血脂异常有关的疾病。

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