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Synthetic intermediate of maxacalcitol, preparation method therefor and use thereof
Synthetic intermediate of maxacalcitol, preparation method therefor and use thereof
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机译:玛沙骨化醇的合成中间体,其制备方法和用途
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摘要
The present invention provides a new method for synthesizing maxacalcitol and an intermediate thereof. According to the method, the maxacalcitol is creatively synthesized through the steps of: taking vitamin D2 as an initial raw material, obtaining a compound represented by formula II, oxidizing, chirally reducing, grafting with a side chain, introducing a hydroxyl group on the C-1 position, and photochemically overturning.
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