Neurotoxicity in human pluripotent stem development based on model prediction

摘要

The present invention relates to the method for three-dimensional (3D) tissue constructs and using this 3D tissue constructs for screening neurotoxic reagent. Particularly, methods provided herein produces and the use of the complicated and consistent tissue phantom of height includes physiology relevant cell, in the application of the required quantitative high frequency zone of the uniformity and reproducibility of the degree of tissue sample model.