FORMULATION OF TENODOVIR LOADED SOLID LIPID NANOPARTICLES USING BIOLIPID FROM COCOA BUTTER

摘要

The current invention explain novelistic method isolation of lipid fraction from cocoa butter and its characterizations and this invention also explain methodology for isolation and preparation of tenofovir loaded solid lipid nanoparticles using biolipid fraction from cocoa butter, stabilizing agent and other co processing agent .the biolipid ! fraction was isolated from the cocoa butter by simplify economical method and subjected I-' for its UV ,IR,DSC and SEM analysis in order to confirm the structure, the tenofovir loaded d solid lipid nanoparticle prepared by using hot sonication technique. The formulation were significant retards for extended period of 36 hrs.