DETECTION OF RITUXIMAB IN PLASMA SAMPLE

摘要

The present invention discloses a method for detecting rituximab in a rheumatoid factor positive human plasma sample, wherein the method employs the use of polyoxyethylene sorbitan mono laurate in an assay diluent buffer, which reduces non-specific binding/interactions in the assay, leading to a greater sensitivity of the assay. Additionally, the method is able to detect rituximab present in relatively lower amounts in unprocessed plasma sample.