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A novel easai method for preparing nanoparticles of high energetic compounds

机译:一种制备高能化合物纳米粒子的新型easai方法

摘要

A part of the invention related to the development of a novel process for the preparation of nanosized particles of high energetic compounds. The novel, Evaporation Assisted Solvent. Antisolvent Interaction (EASAI) method is used for preparing the nano-HECs well below 100 nm. The particle size and shape can be tuned by varying the parameters such as solvent, antisolvent, and temperature of antisolvent and ratio of solvent to antisolvent, rate of stirring and concentration of the HECs. Particles of HECs such as RDX and HMX having average particle size below 100 nm with spherical morphology can be achieved. Hence EASAl method is suitable for preparation of HEC nanoparticles with particles size below 100 nm. The method can also be used for preparing nanoparticles of other organic compounds such as drugs.
机译:本发明的一部分涉及开发用于制备高能化合物的纳米尺寸颗粒的新颖方法。新颖的蒸发辅助溶剂。使用抗溶剂相互作用(EASAI)方法制备远低于100 nm的纳米HEC。可以通过改变诸如溶剂,抗溶剂和抗溶剂的温度以及溶剂与抗溶剂的比例,搅拌速率和HEC的浓度之类的参数来调节粒度和形状。可以获得具有球形形态的平均粒径小于100nm的HEC的颗粒,例如RDX和HMX。因此,EASAl方法适合于制备粒径小于100nm的HEC纳米颗粒。该方法也可以用于制备其他有机化合物例如药物的纳米颗粒。

著录项

  • 公开/公告号IN2015DE03939A

    专利类型

  • 公开/公告日2017-04-07

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN3939/DEL/2015

  • 发明设计人 RAJ KUMAR;PRAMOD SONI;DR PREM FELIX SIRIL;

    申请日2015-12-03

  • 分类号A61B5/55;

  • 国家 IN

  • 入库时间 2022-08-21 13:38:46

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