A KIT FOR RAPID DIAGNOSIS OF MALARIA FROM HUMAN URINE AND METHOD OF DETECTING THE SAME

摘要

This invention relates to a detection kit for rapid malaria diagnosis from urine samples and in particular, this invention relates to rapid immunochromatographic test of antigens inurine indicative of malaria caused by both Plasmodium falciparum and Plasmodiun vivax species. The present invention relies on the fact that in clinical malaria, febrile patients shed elevated levels of rifin family of variant surface antigens proteins, including (PFNF135J)4387) gene specific for P. falciparum and (PVIIG_02112) gene specific for P. vivax, in urine and the test detects those proteins shed in the urine of individuals infected with malaria using monoclonal antibodies against them. Furthermore, the present invention refers to a method for the production of the kit and the use of this kit for the rapid detection of malaria from non-invasive sample urine. This invention also relates to the detection kit which is convenient and fast for operation, is suitable for on-site detection, and is high in specificity, detection sensitivity, accuracy, and reliability and application prospect is promising.