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PREPARATION OF A SOLID FORM OF GADOBENATE DIMEGLUMINE.
PREPARATION OF A SOLID FORM OF GADOBENATE DIMEGLUMINE.
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机译:固态的高苯二酸酯二甲胺的制备。
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摘要
The present invention relates to a process for the preparation of a solid form of the gadobenate dimeglumine compound that comprises obtaining a solution of the said compound in a suitable solvent A wherein the amount by weight of the water optionally present in the solution is at most equal to or lower than the amount by weight of the gadobenate dimeglumine comprised in the solution and adding the obtained solution to an organic solvent B, acting as an appropriate antisolvent and favoring the formation of a solid form of the gadobenate dimeglumine that can be collected by filtration.
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