首页> 外国专利> TRIAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS.

TRIAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS.

机译:三唑衍生物作为GABA受体的配体。

摘要

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, u,v, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. The active compounds of present invention have affinity and selectivity for the GABA A a5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.
机译:本发明涉及其中A,X,Y,u,v,R 1,R 2和R 3如本文所述的式(I)的新三唑化合物及其药学上可接受的盐。本发明的活性化合物对GABA A a5受体具有亲和力和选择性。此外,本发明涉及式(I)化合物的制备,包含它们的药物组合物及其作为药物的用途。

著录项

  • 公开/公告号MX345544B

    专利类型

  • 公开/公告日2017-02-03

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG;

    申请/专利号MX20130004814

  • 发明设计人 ANDREW THOMAS;STEPHEN DEEMS GABRIEL;

    申请日2011-11-02

  • 分类号C07D403/12;A61K31/4155;A61K31/4192;A61K31/427;A61P25/28;C07D405/14;C07D413/14;C07D417/06;C07D417/14;

  • 国家 MX

  • 入库时间 2022-08-21 13:37:29

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号