COMPOSITIONS USEFUL FOR TREATING NEUROPATHIC PAIN, WHICH COMPRISE ENDOGENOUS ANTAGONISTS OF THE N-METHYL-D-ASPARTATE RECEPTOR AND INHIBITORS OF THE ORGANIC ACIDS CARRIER.

摘要

The present invention describes compositions that comprise an endogenous antagonist of the N-methyl-D-aspartate receptor and an inhibitor of the organic acids carrier, such as kynurenine with probenecid, which result very useful and effective for an effective treatment of neuropathic pain without side effects in the motor activity. The compositions of the invention reduce the excretion of kynurenic acid and promote the accumulation in the central nervous system, which results useful for treating the neuropathic pain.