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In signaling storm enhanced traffic management
In signaling storm enhanced traffic management
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机译:在信令风暴中增强流量管理
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摘要
Refers to - 1.2 cyclopentane derivative compounds of formula (i) wherein R1 is heteroaryl of 5 or 6 members optionally substituted; l is a Link, CH2, among others, ra and RB are each h,C1 - C3 alkyl or haloalquilo C1 - C3; R2 is H, alkyl or cycloalkyl C1 - C6 C3 C6; R3 is phenyl or heteroaryl of 5 or 6 members optionally substituted; X is CH2 and CF2, CHF.Preferred compounds are: 2.6 - Dimethoxy - N - [(1S, 2S) - 2 - {[5 - (trifluoromethyl) pyridin-2-yl] amino} ciclopentil] benzamide; 2.6 - Dimethoxy - N - [(1S,(2S) - 2 - [5 - (trifluoromethyl) pyrimidin-2-yl] amino} - 2 - il ciclopentil] benzamide; among others. It also relates to a Pharmaceutical composition.These compounds are useful as Orexin Receptor Antagonists in the treatment of schizophrenia
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