Estereoquimicamente Enriched compositions for Administration of nucleic acids

摘要

Refers to a composition comprising one or more Chemical Entities of a compound of formula I, or a Salt, solvate a solvate of the Salt. This composition is characterized in that more than one Compound of the formula I is a compound of formula Ia, present in a quantity of 50%; or compounds of Formula 1 are present in quantity of 25%, or compounds of formula.2, present in the amount of 25%. This composition is used for the Administration of mRNA in vivo