首页> 外国专利> A novel aryl-3,4-dihydro-2(1H)-thione derivative and a method for preparing aryl-3,4-dihydro-2 (1H)-thione

A novel aryl-3,4-dihydro-2(1H)-thione derivative and a method for preparing aryl-3,4-dihydro-2 (1H)-thione

机译:一种新型的芳基-3,4-二氢-2(1H)-硫酮衍生物和制备芳基-3,4-二氢-2(1H)-硫酮的方法

摘要

the subject of the invention is a new derivative arylo - 3,4 - dihydropirymidyno - 2 (1h) - tionu, which is 4.5 - diarylo substituted derivative of 3,4 - dihydropirymidyno - 2 (1h) - tionu model and where the substituent r means hydrogen atom or group alkilowu0105 c1 - c6 or ch2ar or ar, where ar is formula ii, where x ozn acza carbon atom or nitrogen, and z1, z2.z3 means hydrogen or fluorine atom atom or chlorine atom or group alkilowu0105 c1 - c6 or alkoksylowu0105 c1 - c6 or aryloksylowu0105 or group or a group or a group sililoksylowu0105 acyloksylowu0105 alkenylowu0105 c1 - c6 or arylowu0105 connected by one carbon atom or group arylowu0105 combined by two ato we carbon atoms, comprising associated with z1 and z2 or z2 and z3.the invention also includes a method of manufacturing arylo - 3,4 - dihydropirymidyno - 2 (1h) - tionu, which is to link the relationship litoorganicznego solution eterowym pirymidyno - 2 (1h) - tionu. way is characterized by the fact that arylowy relationship litoorganiczny arli combines with dissolved in solution eterowym 5 - arylopirymidyno - 2 (1h) - tionem, who holds a group r at the nitrogen atom n (1).r is a hydrogen atom or a group alkilowu0105 c1 - c6 or ch2ar or ar, where ar is formula ii, where x is carbon or nitrogen atom, z1, z2,z3 means hydrogen or fluorine atom atom or chlorine atom or group alkilowu0105 c1 - c6 or alkoksylowu0105 c1 - c6 or aryloksylowu0105 or group or a group or a group sililoksylowu0105 acyloksylowu0105 alkenylowu0105 c1 - c6 or arylowu0105 connected by one carbon atom or group arylowu0105 combined by two ato we carbon atoms, comprising associated with z1 and z2 or z2 and z3.the reaction results in temperature from - 20u00b0c to 20u00b0c, and mixed with 10 - 50 minutes, receiving 4.5 - diaryl substituted 3,4 - dihydropirymidyno - 2 (1h) - tionu model and where the substituent r means hydrogen atom or group alkilowu0105 c1 - c6 or ch2ar or ar, where ar is formula ii.
机译:本发明的主题是新的衍生物芳基-3,4-二氢吡mid基-2(1h)-tionu,它是4.5-3,4-二氢吡pi基-2(1h)-tionu模型的二芳基取代的衍生物,其中取代基r表示氢原子或烷基基团 u1105 c1-c6或ch2ar或ar,其中ar是式ii,其中x ozn acza碳原子或氮原子,而z1,z2.z3表示氢或氟原子原子或氯原子或基团 u0105 c1-c6或alkoksylow u0105 c1-c6或芳基okylow u0105或基团或基团或基团sililoksylow u0105 acyloksylow u0105链烯基ow u0105 c1-c6或arylow u0105通过一个碳原子或基团arylow u0105连接碳原子的两个原子,包括与z1和z2或z2和z3缔合的碳原子。本发明还包括一种制备芳基-3,4-二氢吡喃基亚胺基2(1h)-tionu的方法,该方法将联系litoorganicznego溶液eterowym pirymidyno-2(1h)-tionu。这种方式的特点是,亚里基关系Litoorganiczny arli与溶解在溶液中的化合物eterowym 5-arilopirymidyno-2(1h)-tionem结合,该基团在氮原子n(1)上具有基团r。r是氢原子或基团式中,ar是式ii,其中x是碳或氮原子,z1,z2,z3表示氢或氟原子原子或氯原子或基团烷基u0105 c1-c6或aryloksylow u0105或基团或基团或基团sililoksylow u0105 acyloksylow u0105烯基低级 u0105 c1-c6或arylow u0105由一个碳原子或芳基基团lowlow u0105连接而成的两个碳原子,该反应导致温度从-20 u00b0c到20 u00b0c,并混合10-50分钟,得到4.5-二芳基取代的3,4-二氢吡喃基-2(1h)- tionu模型,其中取代基r表示氢原子或烷基基团 u1105 c1-c6或ch2ar o r ar,其中ar是式ii。

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