3-(4-nitrophenyl)-4-(pyridyn-2-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione and method for obtaining it and pharmaceutical composition

摘要

the object of the application is a new 3 - (4-nitrophenyl) - 4 - (pyridin-2-yl) - 4,5 - dihydro 1h 1,2,4 triazolo - 5 - mutation (model 1) and the way to obtain, which is a reaction cyklizacji 4 - (4-nitrophenyl) - 1 - (pyridin - 2 - karbonylotio yl) - semicarbazide (model 2) in a solution of 2% of sodium hydroxide.the mixture is heated in september for about 2 hours, and the sludge is obtained by wytracenie by 3m hcl. the 4 - (4-nitrophenyl) - 4 - (pyridin-2-yl) - 4,5 - dihydro 1h 1,2,4 triazolo - 5 - mutation (model 1) crystallizes, preferably with methanol.which is also the subject of pharmaceutical composition contains as an active ingredient compound 3 - (4-nitrophenyl) - 4 - (pyridin-2-yl) - 4,5 - dihydro 1h 1,2,4 triazolo - 5 - mutation.