SOLID PHARMACEUTICAL COMPOSITION, COMPRISING DONEPEZIL HYDROCHLORIDE OF THE CRYSTALLINE POLYMORPHOUS FORM I

摘要

The present invention relates to a solid pharmaceutical composition, comprising donepezil hydrochloride of the crystalline polymorphous form I. In order to provide a solid pharmaceutical composition in which the donepezil hydrochloride of the crystalline polymorphous form I is stable over a relatively long time period, a solid pharmaceutical composition is proposed, comprising donepezil hydrochloride of the crystalline polymorphous form I and an alkaline-earth metal salt of orthophosphoric acid.