Procedure for establishing biomimetic in vitro model of bladder cancer and use thereof

摘要

the object of the invention, which belongs to the field of tissue engineering, the process of the development of biomimetiu010dnega in vitro model of bladder cancer.following the procedure described for the in vitro model biomimetiu010dnega bladder cancer using in vitro, in normal swine urotelij with inconclusive urotelijskimi differentiated superficial cells (5), on which the fluorescent labeled human bone cancer invasive hours otelijske cells (6).the model allows for the monitoring of cancer cells on the surface of pritrjanja urotelijskih inconclusive differentiated urotelija and their vrau0161u010danja during normal urotelijske in live cells, as well as the analysis of cellular structures after fixation and imunooznau010devanju.the present biomimietiu010dni model represents a unique in vitro model for both basic and applied (testing of nanotechnology based diagnostic approaches as well as preclinical studies (testing of various anticancer agents and the development of potential new drugs).