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Bacterial strain of streptomyces carnosus producing loboforins and loboforin produced by it.

机译:产生loboforins的肉食链霉菌细菌菌株及其产生的loboforin。

摘要

Streptomyces carnosus bacterial strain producing loboforins and loboforin produced by it. # The invention provides a new bacterial strain of Streptomyces carnosus that has been isolated from its natural environment and deposited in the Spanish Type Culture Collection under accession number 9162, which is capable of efficiently producing by fermentation antibiotic compounds of the loboforin family. Specifically, this strain is a producer of a new loboforin, designated in the present invention as loboforin K, which exhibits cytotoxic activity against tumor cells, preferably human, and antibiotic or antibacterial activity against Gram-positive pathogenic bacteria, preferably human.
机译:产罗伯福林的肉链霉菌细菌菌株和由其产生的罗伯福林。本发明提供了一种新的链霉菌细菌菌株,其已从其自然环境中分离出来并以登录号9162保藏在西班牙典型培养物保藏中心,其能够通过发酵产生loboforin家族的抗生素化合物。具体而言,该菌株是新的loboforin的产生者,在本发明中称为loboforin K,其对肿瘤细胞(优选为人)表现出细胞毒活性,并对革兰氏阳性病原细菌(优选为人)表现出抗生素或抗菌活性。

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