a new strain of streptomyces sp. bacterial skin called tn272 produced simultaneously at least eighteen biomolecules with therapeutic interest. agriculture and agri food isomeres cyclic lipopeptides, five of which have never been described

摘要

the present invention relates to a new strain of the genus streptomyces bacterial skin called tn272, isolated from tunisian soil and selected for its ability to inhibit the growth of gram positive bacteria was gram negative, and fungi.after identification of the strain and optimization of the conditions for the production of biomolecules, a protocol for extraction and purification using liquid culture of the strain, eighteen pure biomolecules (m1 - m10) and (l1, l8) has been developed.these biomolecules have been characterized chemically by several spectroscopic techniques and by comparison with the data bank. the biomolecules may be of therapeutic interest and / or agricultural and / or food.the originality of this research is that it produces at the same time these biomolecules including five isomeres of cyclic lipopeptides (14 - 18), with a mass mw, which never were described.