A compound of the formula: ** Formula ** wherein: Y is alkanediyl (C = 8), alkenodiyl (C = 8), alkynediyl (C = 8), or a substituted version of any of these groups; Ra is: hydrogen, hydroxy, halogen, amino, nitro, cyano, azido, phosphate, 1,3-dioxoisoindolin-2-yl, mercapto or silyl; or alkyl (C = 12), alkenyl (C = 12), alkynyl (C = 12), aryl (C = 12), aralkyl (C = 12), heteroaryl (C = 12), heteroaralkyl (C = 12), acyl (C = 12), alkoxy (C = 12), alkenyloxy (C = 12), alkynyloxy (C = 12), aryloxy (C = 12), aralkoxy (C = 12), heteroaryloxy (C = 12), heteroaralkoxy (C = 12), acyloxy (C = 12), alkyl amino (C = 12), dialkylamino (C = 12), alkenylamino (C = 12), alkynyl-amino (C = 12), arylamino (C = 12), aralkylamino (C = 12), heteroaryl-amino (C = 12), heteroaralkylamino (C = 12), alkylsulfonylamino (C = 12), amido (C = 12), alkylthio (C = 12), alkenylthio (C = 12), alkynylthio (C = 12), arylthio (C = 12), aralkylthio (C = 12), heteroarylthio (C = 12), heteroaralkylthio (C = 12), acylthio (C = 12), thioacyl (C = 12), alkylsulfonyl (C = 12), alkenylsulfonyl (C = 12), alkynylsulfonyl (C = 12), arylsulfonyl (C = 12), aralkylsulfonyl (C = 12), heteroarylsulfonyl (C = 12), heteroaralkylsulfonyl (C = 12), alkylsulfinyl (C = 12) , alkenylsulfinyl (C = 12), alkynylsulfinyl (C = 12), arylsulfinyl (C = 12), aralkylsulfinyl (C = 12), h heteroarylsulfinyl (C = 12), hetero-aralkylsulfinyl (C = 12), alkylphosphonylol (C = 12), alkylphosphate (C = 12), dialkylphosphate (C = 12), alkylammonium (C = 12), alkylsulfonium (C = 12), alkylsilyl (C = 12), or a substituted version of any of these groups; or Y and Ra form a 3- to 7-membered ring, so that Y and Ra are further connected to each other by one or more of -O- and (C1-5) alkanediyl, where in addition Y is -CH- and Ra is -CH2-; or Y, Ra, and carbons number 13, 17, and 18 form a ring, so that Ra is attached to carbon 13, where Y is substituted alkanediyl (C = 1) or substituted alkanediyl (C = 1) and Ra is - OR-; wherein the term "alkenyl" when used without the "substituted" modifier refers to a monovalent group with a non-aromatic carbon atom as the point of attachment, having a linear or branched, cyclic, cyclic or acyclic structure, at least one non-aromatic carbon-carbon double bond, without carbon-carbon triple bonds, and without atoms other than carbon and hydrogen; wherein the term "substituted alkenyl" refers to a monovalent group with one non-aromatic carbon atom as the point of attachment, at least one non-aromatic carbon-carbon double bond, without carbon-carbon triple bonds, having a linear structure or branched, cyclic, cyclic or acyclic, and at least one atom independently selected from the group consisting of N, O, F, Cl, Br, I, Si, P and S; wherein the term "alkynyl" when used without the "substituted" modifier refers to a monovalent group with a non-aromatic carbon atom as the point of attachment, having a linear or branched, cyclic, cyclic or acyclic structure, at least one carbon-carbon triple bond, and without atoms other than carbon and hydrogen; wherein the term "substituted alkynyl" refers to a monovalent group with a non-aromatic carbon atom as the point of attachment and at least one carbon-carbon triple bond, having a linear or branched, cyclic, cyclic or acyclic structure , and at least one atom independently selected from the group consisting of N, O, F, Cl, Br, I, Si, P and S; wherein the term "aryl" when used without the "substituted" modifier refers to a monovalent group with an aromatic carbon atom as the point of attachment, said carbon atom being part of a 6-membered aromatic ring structure, where the ring atoms are all carbon, and where the monovalent group consists of atoms other than carbon and hydrogen; wherein the term "alkyl group" includes alkyl groups that may contain one or more cycloalkyl components; wherein the required hydrocarbon components of the alkanediyl, alkenodiyl, and alkynediyl groups include hydrocarbon components, which may contain one or more carbocyclic moieties; wherein the alkyl parts of the alkoxy, alkylamino, alkylimino, alkylthio, alkylsulfonyl, alkylsulfinyl, alkylammonium and alkylsulfonium groups include alkyl parts which may contain one or more cycloalkyl components; or one of its pharmaceutically acceptable salts or tautomers.
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