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Biomarker for mental disorders, including cognitive disorders, and method of using said biomarker for the detection of mental disorders, including cognitive disorders

机译:包括认知障碍在内的精神疾病的生物标志物,以及使用所述生物标志物检测包括认知障碍在内的精神障碍的方法

摘要

Peptide or protein for use as a biomarker for the detection of psychiatric diseases or cognitive impairment, in which the protein is a precursor to neurexin-2-beta consisting of the amino acid sequence expressed by SEQ ID No. 1 or the protein it is a protein consisting of the amino acid sequence obtained from SEQ ID No. 1 by deletion, exchange and / or addition of one to three amino acids, and the peptide is the NRX2B peptide derived from a neurexin-2-beta precursor that It consists of the amino acid sequence expressed by SEQ ID No. 2 or the peptide is a peptide consisting of an amino acid sequence derived from SEQ ID No. 2 by deletion, exchange and / or addition of one to three amino acids.
机译:用作检测精神疾病或认知障碍的生物标记物的肽或蛋白质,其中该蛋白质是神经毒素-2-β的前体,该蛋白由SEQ ID No. 1表示的氨基酸序列组成,或者是该蛋白质由通过缺失,交换和/或添加1至3个氨基酸而从SEQ ID No.1获得的氨基酸序列组成,并且该肽是衍生自neurexin-2-beta前体的NRX2B肽,由由SEQ ID No.2表达的氨基酸序列或该肽是由通过缺失,交换和/或添加1-3个氨基酸而衍生自SEQ ID No.2的氨基酸序列组成的肽。

著录项

  • 公开/公告号ES2617918T3

    专利类型

  • 公开/公告日2017-06-20

    原文格式PDF

  • 申请/专利权人 MCBI INC.;

    申请/专利号ES20100777546T

  • 申请日2010-05-17

  • 分类号G01N33/68;C07K14/47;G01N21/78;G01N27/62;G01N33/53;G01N33/543;

  • 国家 ES

  • 入库时间 2022-08-21 13:35:19

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