Taste receptors of the domestic cat family T1R

摘要

An isolated and purified polynucleotide encoding a feline T1R receptor polypeptide and comprising: a) the nucleotide sequence of SEQ ID NO: 1 or SEQ ID NO: 99; b) a variant of the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 99, and said variant has an identity (equality) of at least 98% with respect to the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 99 and encodes a polypeptide that has essentially the same biological activity as a polypeptide encoded by the nucleotide sequence of SEQ 10 ID: 1 or SEQ ID NO: 99; c) a variant of the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 99, and said variant has an identity (equality) of at least 98% with respect to the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 99 and encodes a polypeptide that confers a modified taste perception (modified taste perception) with respect to one or more taste stimuli, compared to a polypeptide encoded by the polynucleotide of SEQ ID NO: 1 or SEQ ID NO: 99; or d) a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 2.