METHODS FOR TREATING PRESSURE INDUCED OPTIC NEUROPATHY, PREVENTING NEURONAL DEGENERATION AND PROMOTING NEURONAL CELL SURVIVAL VIA ADMINISTRATION OF LINGO-1 ANTAGONISTS AND TRKB AGONISTS

摘要

This invention relates to methods for promoting neuronal survival andregeneration using LINGO-1 antagonistsand TrkB agonists. Additionally, the invention relates to methods for treatingpressure induced optic neuropathies using LINGO-1antagonists. The invention also relates generally to methods for increasingTrkB activity and inhibiting JNK pathway signaling usinga LINGO-1 antagonist.