MOSAIC CLADE M ENV-BASED POLYVALENT HIV VACCINE

摘要

The present invention relates, in general, to an immunogenic composition(e.g., a vaccine) and, in particular, to apolyvalent immunogenic composition, such as a polyvalent HIV vaccine, and tomethods of using same. The invention furtherrelates to methods that use a genetic algorithm to create sets of polyvalentantigens suitable for use, for example, in vaccinationstrategies.