CEPHALOSPORINS HAVING CATECHOL GROUP

摘要

The present invention provides Cephem compounds having awide antimicrobial spectrum and potent antimicrobial activityagainst beta-lactamase producing Gram negative bacteria of theformula:(see Formula 1)wherein,X is N, CH or C-Cl;T is S or the like;A and G are lower alkylene or the like;B is a single bond or the like;D is a single bond, -NR7-, -CO-, -CO-NR7-, -NR7-CO-, -NR7-CO-NR7-,or the like;E is optionally substituted lower alkylene;F is a single bond or optionally substituted phenylene;R3, R4, R5 and R6 each is independently hydrogen, halogene,nitrile, or the like;or an ester, a compound protected at the amino on the ring inthe 7-side chain, a pharmaceutically acceptable salt, or asolvate thereof.