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3-PHENYL-3-METHOXYPYRROLIDINE DERIVATIVES AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

机译:3-Phenyl-3-metyoxypyrylidine衍生物作为皮质的儿茶酚胺神经递质的调节剂

摘要

The present invention relates to novel 3-phenyl-3-methoxy-pyrrolidinederivatives, useful for modulating extracellularlevels of catecholamines, dopamine and norepinephrine, in cerebral corticalareas of the mammalian brain, and more specificallyfor the treatment of central nervous system disorders. In other aspects theinvention relates to pharmaceutical compositionscomprising the 3-phenyl-3-methoxy-pyrrolidine derivatives of the invention andto the use of these compounds for therapeutic applications.
机译:本发明涉及新颖的3-苯基-3-甲氧基-吡咯烷衍生物,可用于调节细胞外皮质中儿茶酚胺,多巴胺和去甲肾上腺素的水平哺乳动物大脑区域,更具体地说用于治疗中枢神经系统疾病。在其他方面本发明涉及药物组合物包含本发明的3-苯基-3-甲氧基-吡咯烷衍生物和这些化合物在治疗中的用途。

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