ALPHA-KETOGLUTARATE IN COMBINATION WITH GLUTAMATE DEHYDROGENASE FOR TREATING HYPERAMMONEMIA

摘要

The invention relates to a pharmaceutical composition comprising alpha-ketoglutarate, optionally a glutamate dehydrogenase, and optionally a cofactor for glutamate dehydrogenase. The composition according to the invention is particularly useful for the treatment or prevention of a liver disease, wherein the liver disease is preferably hyperammonemia or a disease associated with hyperammonemia.