METHOD FOR PREDICTING THE RESPONSE TO A TNFRSF6-INFLUENCED CANCER TREATMENT AND FOR PREDICTING RESISTANCE TO A CANCER TREATMENT

摘要

The present invention relates to a method based on differential levels of phospho- TNFSFR6, for screening a patient suffering from a cancer influenced by TNFSFR6 signaling, and who might benefit from a given therapy, comprising: a) a step of detecting the phosphorylation of the residues Y232 and Y291 of TNFRSF6, in a biological sample of said patient; and b) comparing the phosphorylation levels of the residues Y232 and Y291 of TNFRSF6 obtained in step a) to their respective reference levels, in which phosphorylation levels of Y232 et Y291 is indicative of the therapy to be given.