Sugar compositions for treating hemophilia A and/or von Willebrand disease.

摘要

#$%^&*AU2013203347C120170615.pdf#####(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date W O 2013/167303 Al 14 November 2013 (14.11.2013) W I P 0 I P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/70 (2006.01) A61K31/7008 (2006.01) kind of national protection available): AE, AG, AL, AM, A61K31/7004 (2006.01) A61P 7/04 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, ) .a BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, Fl, GB, GD, GE, GH, GM, GT, PCT/EP2013/055474 HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, (22) International Filing Date: KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, 15 March 2013 (15.03.2013) ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, (25) Filing Language: English RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, (26) Publication Language: English TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 12167178.8 8 May 2012 (08.05.2012) EP (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant: CSL BEHRING GMBH [DE/DE]; Emil-von- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, Behring-Strasse 76, 35041 Marburg (DE). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: SCHULTE, Stefan; Bauerbacher Strasse 46, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 35043 Marburg (DE). SPIRIG, Rolf; Landoltstrasse 83, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, CH-3007 Bern (CH). ZOLLNER, Sabine; Talblickstrasse MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 6, 59969 Bromskirchen (DE). MOSES, Michael; Am TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Feldweg 11, 61279 Graevenwiesbach (DE). WORMS- ML, MR, NE, SN, TD, TG). BAECHER, Wilfried; Blumenweg 9, 35274 Kirchhain Published: (DE). STOEHR, Hans-Arnold; Schulstrasse 66, 35083 - with international search report (Art. 21(3)) Wetter (DE). (74) Agents: PETER, Beate et al.; Emil-von-Behring-Strasse 76, 35041 Marburg (DE). (54) Title: SUGAR COMPOSITIONS FOR TREATING HEMOPHILIA A AND/OR VON WILLEBRAND DISEASE (57) Abstract: The invention relates to compositions comprising an isolated sugar for use in the treatment of von Willebrand disease and/or hemophilia A, wherein the sugar is an accessible sugar residue derived from ABO(H)blood group antigen.