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LOSSLESS CRYO-GRID PREPARATION STAGE FOR HIGH-RESOLUTION ELECTRON MICROSCOPY
LOSSLESS CRYO-GRID PREPARATION STAGE FOR HIGH-RESOLUTION ELECTRON MICROSCOPY
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机译:高分辨电子显微镜的无缝冷轧网格制备阶段
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摘要
The invention relates to a preparation system for preparing a sample for electron microscopy, comprising: - a liquid handling system (0) comprising a dispensing head (1), wherein said liquid handling system (0) is configured to aspirate and dispense a volume of a sample via the dispensing head (1), - a support structure (2) that is configured to accommodate the sample, a temperature-controlled stage (4) that is configured to keep said support structure (2) at a pre-defined temperature when the support structure (2) is arranged on the temperature-controlled stage (4), a first adapter (3) configured to hold said support structure (2), a transfer mechanism (60) that is configured to be connected to the first adapter (3) holding the support structure (2) and to move said support structure (2) into a container (8) containing a liquid cryogen (80) so that the sample on the support structure (2) contacts the cryogen (80). Furthermore, the invention relates to a corresponding method.
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