首页> 外国专利> METHOD FOR PROMOTING EXTRACELLULAR MATRIX PRODUCTION, METHOD FOR CULTURING CELLS, AND AGENT FOR PROMOTING EXTRACELLULAR MATRIX PRODUCTION

METHOD FOR PROMOTING EXTRACELLULAR MATRIX PRODUCTION, METHOD FOR CULTURING CELLS, AND AGENT FOR PROMOTING EXTRACELLULAR MATRIX PRODUCTION

机译:促进细胞外基质产生的方法,培养细胞的方法和促进细胞外基质产生的试剂

摘要

The present invention is: a method for promoting extracellular matrix production in cultured cells, the method being characterized by bringing cells that are being cultured into contact with an alicyclic structure-containing polymer molding; a method for culturing cells, the method being characterized by bringing cells that are being cultured into contact with an alicyclic structure-containing polymer molding, and promoting extracellular matrix production by the cultured cells; and an agent for promoting extracellular matrix production in cultured cells, the agent being composed of an alicyclic structure-containing polymer molding. According to the present invention, increasing the amount of extracellular matrix produced by cells makes it possible to increase the amount of protein expressed by foreign protein-producing cells without the use of a culture vessel coated with extracellular matrix.
机译:本发明是:一种用于促进培养的细胞中细胞外基质产生的方法,其特征在于使正在培养的细胞与含有脂环结构的聚合物成型体接触。一种细胞的培养方法,其特征在于,使培养中的细胞与含有脂环结构的聚合物成型体接触,促进培养的细胞的细胞外基质的产生。用于促进培养细胞的细胞外基质生成的试剂由含有脂环结构的聚合物成型体构成。根据本发明,增加细胞产生的细胞外基质的量使得可以增加由外源蛋白质产生细胞表达的蛋白质的量,而无需使用涂覆有细胞外基质的培养容器。

著录项

  • 公开/公告号WO2017010533A1

    专利类型

  • 公开/公告日2017-01-19

    原文格式PDF

  • 申请/专利权人 ZEON CORPORATION;

    申请/专利号WO2016JP70750

  • 发明设计人 ICHIMURA NAOYA;HIRANO TAKAAKI;

    申请日2016-07-13

  • 分类号C12P21/02;C12N5;C07K14/78;C08L45;C12M3;

  • 国家 WO

  • 入库时间 2022-08-21 13:32:41

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