SINGLE-STRANDED DNA SENSOR

摘要

The invention relates to a protein of the single stranded DNA binding domain (SSB) family, wherein said protein is a modified Plasmodium protein, said protein comprising at least one detectable label attached to an amino acid of said protein, wherein said amino acid is located on the (L1-1') loop of residues joining the two beta sheets (β1) and (β1'), wherein the characteristics of the detectable label alter on binding single stranded DNA. The invention also relates to nucleic acids, uses and methods.