USE OF MICRO-RNAS CIRCULATING IN THE BLOOD SERUM OR BLOOD PLASMA FOR IDENTIFYING PATIENTS REQUIRING A BIOPSY AND AS A MARKER FOR THE DIFFERENTIAL DIAGNOSIS OF INDIVIDUAL NON-ISCHEMIC CARDIOMYOPATHIES OR STORAGE DISEASES AFFECTING THE HEART

摘要

The invention relates to the use of certain micro-RNAs circulating in the blood serum or blood plasma in the form of diagnostic profiles as a marker in an in vitro method for distinguishing between patients for which a myocardial biopsy is necessary for the diagnostic identification of a heart muscle disease and patients for which a myocardial biopsy is not necessary, and for the optional differential diagnosis of individual non-ischemic cardiomyopathies or storage diseases affecting the heart.