KETOLIDE ANTIBIOTICS INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
展开▼
机译:中间体中间体酮醚化物及其制备方法及其应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A ketolide antibiotics intermediate, a preparation method therefor, and application thereof in preparation of solithromycin. The ketolide antibiotics intermediate has a compound structural general formula as shown as follows, and can be prepared by using existing raw materials via several simple steps, the reaction operation is simple and convenient, the utilization rates of macrolides pregnant nucleus raw materials and side chain raw materials are high, and the yield is high. When the ketolide antibiotics intermediate is used for compounding of solithromycin, comprehensively compared with the prior art, the purity and the yield are greatly improved, and good practical value is obtained.
展开▼