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BABESIA BIOMARKERS FOR DIAGNOSTIC AND SCREENING IN VITRO DIAGNOSTIC TEST

机译：巴比斯生物标志物的诊断和筛选体外诊断

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摘要

An antigen composition with plurality of antigens from B. microti, and methods of predicting a likelihood of an individual having B. microti infection using the antigen composition as biomarkers of infections of B. microti to human are provided. In particularly preferred aspects, the antigens are immunodominant and have quantified and known relative reactivities with respect to sera of a population infected with the pathogen with an average discriminatory p value of ≤ 0.05. 展开▼

机译：一种具有多种来自的抗原的抗原组合物。 microti ，以及预测个体患有 B的可能性的方法。抗原组合物作为 B感染的生物标志物进行小肠感染。提供了人类的微量滴。在特别优选的方面，所述抗原是免疫显性的，并且相对于感染有病原体的人群的血清具有定量的和已知的相对反应性，其平均鉴别p值≤0.05。 展开▼

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公开/公告号WO2017100598A1

专利类型

公开/公告日2017-06-15

原文格式PDF

申请/专利权人 IMMPORT THERAPEUTICS INC.;
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申请/专利号WO2016US65862

发明设计人 MOLINA DOUGLAS;RANDALL ARLO;HERMANSON GARY;MAMOUN CHOUKRI BEN;
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申请日2016-12-09

分类号C07K14/44;G01N33/569;

国家 WO

入库时间 2022-08-21 13:30:47

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